“YouTube’s Margaret Gould Stewart broke down the appeal of viral videos as this: “Viral videos are always tapping into something human — love, food, sex, failure… Something that people can relate to and share with others.”
via http://gigaom.com/video/viral-video-prediction-2011
Viral videos are just a slice of word of mouth. The same emotive appeal that drives YouTube videos to share wildly will feed word of mouth in any format.